Statins and Effects on Bone

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Current research interests in our laboratory include drug discovery for osteoporosis, fracture repair and other diseases.

In the last few years we have been very interested in the statins and their effects in bone.


Biomech1
BioMech2
Three point bending test of a rat femur with a fracture callus.

The resulting force-deflection curve from a three point bend test provides the biomechanical properties of bone

Projects:

Personnel:

  • Gregory Mundy: Director of the Center for Bone Biology
  • Jeffry Nyman: Instructor: Biomechanical testing and uCT analysis
  • Jianghong Zhang: Staff Scientist: Histology processing
  • Satyawan Jadhav: Postdoctoral fellow: Biodistribution of statins, mechanism of action
  • Rebecca Parker: Research Assistant: Animal care

The VUMC Center for Bone Biology is a member of the VUMC Department of Medicine in the Division of Clinical Pharmacology.



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